EMERITUS FACULTY

Naomi Breslau, PhD

Professor of Epidemiology and Biostatistics
breslau@epi.msu.edu

ISI HighlyCited

Dr. Breslau is a highly cited psychiatric epidemiologist and PhD-trained sociologist who makes major contributions and scientific advances in the epidemiological study of numerous psychiatric conditions and behavioral disturbances, most prominently post-traumatic stress disorder and tobacco dependence.

She also has been an important contributor of epidemiological evidence on long-term effects of low birthweight (e.g., with respect to problem-solving capacities as disclosed by intelligence and other cognitive testing).

She holds multiple NIH research awards, and has been actively involved in development of training programs at MSU. .

(See http://www.isihighlycited.com for more details about Dr. Breslau’s research contributions.)

Janet Osuch, MD

Professor of Epidemiology and Surgery

Michigan State University, Human Medicine, 1979
M.S., Michigan State University, Epidemiology, 2000

janet.osuch@ht.msu.edu

Dr. Osuch, a professor of Surgery and Epidemiology. Janet limited her surgical practice to diseases of the breast from 1987-1998, and founded the Comprehensive Breast Health Clinic at MSU in 1992. She obtained a Master's degree from this department in 2000. She currently teaches and performs research related the etiology and diagnosis of breast cancer, and is developing protocols to investigate outreach methods to improve success of surgical procedures (e.g., sustained tobacco smoking cessation interventions directed toward surgery patients and evaluated through randomized trial methods).

Selected Publications

Hsu WW, Osuch JR, Todem D, Taffe B, O’Keefe M, Adera S, Karmaus W. DDE and PCB serum concentration in maternal blood and their adult female offspring. Environ Res 2014; 132:384-90. Epub 2014 May 17a Department of Statistics, Kansas State University, Manhattan, KS, USA

Osuch JR, Hsu W-W, Todem D, Landfraf J, Karmaus W, Mikucki D, Haan P. Female Reproductive Status and Circulating Blood Leukocyte Expression of Selected Metabolic and Signaling Genes involved in Sex Steroid Metabolism. International Journal of Molecular Epidemiology and Genetics 2012;3(2):134-143. PMID: 22724050.

Osuch JR, Price C, Barlow J, Miller K, Hernick A, Fonfa A. An Historical Perspective on Breast Cancer  Activism in the United States: From Education and Support to Partnership in Scientific Research.  J Womens Health 2012 Mar;21(3): 355-362. Epub 2011 Dec 1. PMID: 22132763.

Warner J, Osuch JR, Karmaus W, Landgraf J, Taffe B, O’Keefe M, Mikucki D, Haan P. Common Clasification Schemes for PCB Congeners and the Gene Expression of CYP 17, CYP19, ESR1 and ESR2. Sci Total Environ 2012 Jan1; 414:81-89. Epub 2011 Nov 23. PMID: 22119029.

A. Mahdi Saeed, DVM, MPH, PhD

Professor of Epidemiology and Biostatistics

DVM. 1973, University of Baghdad
Ph.D. Washington State University
MPH. University of Washington School of Public Health and Community Medicine
Dipl, (ACVPM)

E-mail: saeeda@msu.edu

Dr. Saeed has been conducting research on food safety and prevention of foodborne diseases, zoonotic diseases and their impact on human populations. Assesment of the role of exposure to animals in the developmnent of zoonotic diseases such as Campylobacteriosis and salmonellosis. Developing, with other professionals, state-wide programs in food safety epidemiology and emerging infectious diseases. Development of new courses in food safety epidemiology for a new food safety specialty degree at Michigan State University.

Selected Publications

Aref. NM and Saeed. AM. Design and Characterization of highly immunogenic heat-stable enterotoxin of nterotoxigenic Escherichia coli K99”. Journal of Immunological Methods. 366 (2011) 100-105.

Aref. NM and A Mahdi Saeed. 2012. An enhanced protocol for expression and purification of heat-stable enterotoxin of Enterotoxigenic Escherichia coli. Journal of biochemical and molecular toxicology 2012; 26(4):168-75.

Aref. NM and A Mahdi Saeed. 2012. Generation of high-titer of neutralizing polyclonal antibodies against heat-stable enterotoxin (STa) of Enterotoxigenic Escherichia coli. Vaccine 2012;30 (45):6341-6.

Abdulla. AA, Abdullkreem alkazaz, Alice K. Melconian, Mahdi Saeed*. 2012. Design and Evaluation of a Recombinant Flagellin-based Putative Vaccine from Salmonella Typhimurium DT104. Inter. J Biotech Adv. 1(1): 1-6.

Zahid Butt, Melinda Wilkins, Elizabeth Hamilton, David Todem, Joseph Gardiner, and Mahdi Saeed. Hepatitis B and Hepatitis C co-infections in HIV/AIDS population in the state of Michigan. 2013. Epidemiology and Infection. February. Pages 1-8.

Zahid Butt, Melinda Wilkins, Elizabeth Hamilton, David Todem, Joseph Gardiner, and Mahdi Saeed. Mortality among HIV-hepatitis co-infected individuals in the state of Michigan. Epidemiology and Infection. 2013. November. Pages: 1-9

Arshad. MM and AM. Saeed*. 2013. Antimicrobial Resistance among Salmonella Enteritidis Isolates from Egg lying Flocks in the United States. IJAPR Vol.1 pp:1-6.

Nguyen. C, S. Cho, and A.M. Saeed*. Epidemiologic Attributes and Virulence Profile of Salmonella Tennessee isolates from Infections associated with Peanut Butter National Outbreak, United States, 2006-2007. Journal of Biology, Agriculture and Healthcare. 2013. Vol : No.17. PP : 36-42.

Arshad. MM and AM. Saeed*. 2013. Antimicrobial Resistance among Salmonella Enteritidis Isolates from Egg lying Flocks in the United States. IJAPR Vol.1 pp: 1-6.

 Abdulla. AA, Arshad. MM, and A. Mahdi Saeed2*.2014. Salmonella Enteritidis Flagella may Enhance Attachment and Invasion of Hen Ovarian Granulosa Cells and Induce Protective Immune Response in Egg-laying Hens. British Microbiology Research Journal. 2014. Vol:4. No.4. pp: 418-427.

Abdulla1. AA, Thikra A. Abed. TA, and Saeed*AM. 2014. Adhesion, Autoaggregation and Hydrophobicity of Six Lactobacillus Strains. British Microbiology research Journal. 4 (4). 381-391.

Aziz. IF, Azeez. GM, Ad'hiah AH, Mahdi Saeed A. 2014. Production of Recombinant Heat Shock
Protein 60 (HSP60) from Salmonella enteric serovar Typhimurium ATCC 19585 and Its Evaluation  as a Vaccine Candidate in BALB/c Mice. J Microb Biochem Technol 6: 346-350.

Zahid Butt, Melinda Wilkins, Elizabeth Hamilton, David Todem, Joseph Gardiner, and Mahdi Saeed. Spatial analysis of Hepatitis B and Hepatitis C co-infection in HIV/AIDS population in the state of Michigan. 2013. (under preparation).

Saeed*, AM, Egg yolk-derived antibodies may have a higher avidity to the Escherichia coli heat stable enterotoxin than rabbit serum antibodies. (Under preparation).

Saeed*AM and Aref. NM. Characterization of specific and neutralizing antibody for Escherichia coli heat stable enterotoxin derived from egg yolk from eggs laid by hens immunized with the immunogenic STa enterotoxin ( under preparation).

Francis. M, Todem. D, Wirth. J., Saeed.AM. Modeling of the Immune response to a novel vaccine to Enterotoxigenic E. coli Heat- Stable enterotoxin in. (under preparation).

Saeed*AM and Aref. NM. Characterization of specific and neutralizing antibody for Escherichia coli heat stable enterotoxin derived from egg yolk from eggs laid by hens immunized with the immunogenic Sta enterotoxin ( under preparation).

Nguyen, S. Cho , K. Evon , D.J. Boxrud , S.C. Rankin , M. Wiedmann , F. Downe , J. Lovchik , D. Smalley, M. Erdman , and A.M. Saeed*. Genomic and virulence assessment of Salmonella Tennessee Associated with the 2006/2007 national peanut butter outbreak. (under preparation).

Julie Wirth, PhD

Assistant Professor of Epidemiology and Biostatistics

Ph.D. Thomas Jefferson University, Microbiology, 1979
M.S., Michigan State University, Epidemiology, 2001
Email: wirthj@msu.edu

Dr. Wirth is a PhD microbiologist with graduate training in epidemiology, whose current primary research focus is the study of exposures to organochlorines and male reproductive health. She also is expert in research on environmental chemicals and human health generally, and is studying gene-environment interactions using epidemiological and microbiological research approaches.

Dr. Wirth helps to link the department faculty and students with the Michigan Department of Community Health’s epidemiological research activities.