BMPES
(Blantyre Malaria Project Epilepsy Study)

Gretchen Birbeck, PI

CPON

The Cerebral Palsy Outreach Network (CPON) is an internet resource for children with cerebral palsy (CP) and their families.  The mission of CPON is to help families connect to needed services, to provide scientific information to families on new treatments for CP, and to develop research on the causes and management of CP. A case-control study of CP in Michigan will be resubmitted to NIH on March 1, 2006.

Nigel Paneth, PI. Madeleine Lenski Project manager

CDC Autism

Data Coordinating Center for Autism & Other Disabilities                                                                                

The purpose of this cooperative agreement, with CDC, is for the Michigan State University Data Coordinating Center (MSU-DCC) to serve as a data coordinating center for a multicenter study to support surveillance data and research data management related to developmental disabilities, such as Autism Spectrum Disorders(ASD) and other Developmental Disabilities (DD).

Hossein Rahbar, PI

ChEAFS

(Chikankata Epilepsy and Febrile Seizure Study)

Gretchen Birbeck, PI

D43- ICHORTA

With this application, the directors and the faculty of a NIDA-supported T32 institutional research training program on drug dependence epidemiology seek to enhance the international research and research training capacities of the training program, NIH, NIDA and Fogarty International Center.  This project will link faculty and students of the Bloomberg School of Public Health with the Universidad Peruana Cayetano Heredia in Lima, Peru.

Jim Anthony, PI

Effect of Organochlorides on Male Infertility

This study will investigate the relationship between measure of human male reproductive health, specifically semen quality and reproductive hormone levels, organochlorine compound environmental contaminants and polymorphisms in genes involved in contaminant and sex steroid metabolism

Julie Wirth, PI

ELGAN

Extremely Low Gestational Age Newborns (ELGAN) is a large multi-regional study investigating biochemical antecedents of brain damage in newborns (under 28 weeks).  MSU is the coordinating center for enrollment and data-collection at four hospitals in the Lake Michigan hub.  We have enrolled 1,500 babies and developmentally assessed 85% of those who have reached 12 and 24 months.   We are now moving into ELGAN II, which will follow up these babies at age 5 years, and the proposal to NIH will be submitted Feb 1, 2006.

Nigel Paneth, PI   

EASZ

(Epilepsy-associated Stigma in Zambia Study)

Gretchen Birbeck, PI

FIRCA

Clusters of Drug Involvement in Chile (FIRCA)

This is a collaborative, epidemiological research project studying the earliest stages of youthful drug involvement, including coca paste and other cocaine use in Chile.

Jim Anthony, PI  

FRIENDS

There is a lot of concern today about chemicals in the Fox River and other lakes and rivers near Green Bay.  These chemicals, called PCBs, build up in the fat of fish that live in contaminated lakes and rivers.  People who eat this fish also have PCBs in their bodies.  The goal of the FRIENDS project is to find out how much locally caught fish Hmong and Lao families eat, and if people who eat fish with PCBs have more health problems than people who don’t eat this fish. 

http://www.cvm.uiuc.edu/vb/friends_center/

Great Lakes Fisheater Study

Federally funded project assessing cognitive functioning in aging members of the Michigan Department of Community Health’s Lake Michigan Anglers cohort. 

Joseph Gardiner, PI

HRSA 

Multi-level analysis of disparities in Preterm Delivery

The purposes of the HRSA contract is to expand the use of multi-level modeling as a tool for examining the influences of neighborhood context on the risk of delivering prematurely, to disseminate examples of the analysis and develop strategies for instructing state and local maternal and child health (MCH) professionals on the value of contextual level variables and multi-level modeling, and help them to identify avenues for training in multi-level statistical techniques.

Claudia Holzman, PI

IRBS/DISC: 

Insulin-Related Biomarkers Study in the Dietary Intervention Study in Children

An energy-dense diet high in fats and refined carbohydrates and low in fiber in young girls has been linked to earlier age at menarche and taller adult height, both of which have been associated with increased risk for breast cancer.  We are conducting longitudinal analyses to examine the effect of a low-fat dietary intervention in 8-10 year old girls, specific dietary constituents and physical activity, on the insulin-related growth factor (IGF)-axis, as well as insulin in girls throughout adolescence.

Ellen Velie, PI

K-Award:  Drug Dependence

Drug Dependence Epidemiology and Enviromics

To combine enviromics, genetics, and epidemiology in research on drug dependence syndromes.

Jim Anthony, PI

K-Award:  Energy Balance and Breast Cancer

This National Cancer Institute, Division of Cancer Prevention funded career award provides salary and research assistance support for career development activities and the conduct of three research projects.  The goal of this work is to examine the relationship between energy balance and insulin resistance-related factors over the lifecourse on the age-specific incidence of breast cancer in black and white women in the United States. 

Ellen Velie, PI

MASCOTS

The Michigan Acute Stroke Care Overview & Treatment Surveillance System (MASCOTS)  is
a representative, statewide, hospital-based surveillance system of acute stroke care in Michigan.

Mat Reeves, PI

www.epi.msu.edu/mascots

OSSM

OSSM was inherited from Dr. Wilfried Karmaus.  Its goal is to examine the association between organochlorine exposure and mRNA expression of sex steroid metabolites in female offspring of the original fisheater's project.  The project is currently in the recruitment phase.

Janet Osuch, PI  

Perinatal Epidemiology Training Program

Trains pre and postdoctoral students in perinatal epidemiology. 

Nigel Paneth, PI.

Polish Women Health Study

This international study looks at the “Effect of Changes in Diet and Other Factors on Breast Cancer Risk of Women Immigrants from Poland to the United States.”

Dorothy Pathak, PI

POUCH Study

Etiologic Heterogeneity in Preterm Delivery

The aim of this study is to better understand the causes of preterm delivery by identifying the pathways through which risk of preterm delivery is mediated, and the role of maternal serum alpha fetoprotein in these pathways.  Over seeing a Minority Supplement under this grant.

Claudia Holzman, PI

POUCHMoms

Jeanette Scheid PI, Co-PI Claudia Holzman, and Laura Symonds.

RASEP

 Race/Area Socioeconomic Position and Cancer Incidence, Detroit

In this project we are examining the joint effects of racial and socioeconomic characteristics of census tracts of residence on cancer incidence rates in the Detroit Metropolitan Area using data from the US Surveillance, Epidemiology, and End Results (SEER) Detroit cancer registry and the US census.

Ellen Velie, PI

TEAM

The Transient Ischemic Attack, Evaluation and Management (TEAM) Study is being undertaken in 4 emergency departments across MSU's community campuses. The goals of the study are to assess the management, treatment, and prognosis of TIA patients over a 90 day follow-up period.

Mat Reeves, PI

THOP

Transient Hypothyroxinemia of Prematures

We are the data management arm of an international Phase I/II randomized trial of the use of thyroid hormone in infants < 28 weeks gestational age. The data sites are Westchester County, New York (where the PI is), Amsterdam, Holland and Madrid, Spain.   

PI of the data management subcontract is Nigel Paneth, and Hossein Rahbar is the statistician.